Jurgen Klopp made six changes to the side that beat Aston Villa at the weekend as Alex Oxlade-Chamberlain, Divock Origi, Fabinho, James Milner, Joe Gomez and Naby Keita came into the side.
The Reds took the lead in the 14th minute as Origi played in Milner, whose left-footed cross rebounded off a Genk defender and fell to Gini Wijnaldum, who finished superbly with a deft touch from close-range.
Watch All GOALS and Highlights: Liverpool 2-1 Genk
Andy Robertson, Sadio Mane and Roberto Firmino were named on the bench, with perhaps a view to this Sunday’s clash against Manchester City, whilst Jordan Henderson was sidelined due to illness.
The Reds nearly doubled their advantage with 35 minutes gone as Milner found Salah, who ran into the box and sent a powerful strike goalwards, only for the ball to flash wide of the far post.