Samir Handanovic will return in goal for Inter, but Mancini has a number of options if he wants to continue to rotate the rest of his team, with Lukas Podolski potentially being involved after missing out in midweek.
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Viola will be targeting a fourth-place finish in the table, but with a number of teams lining up behind them, including Inter, they will be wary of getting dragged into a tighter battle for a European spot.